Gene information
Official symbol SERPINA5
Official full name serpin family A member 5
Gene type protein-coding gene
Chromosome14q32.13
Alias symbolPAI3; PROCI
Previous symbolPLANH3; PCI
Gene familySerpin peptidase inhibitors
Resources
Entrez Gene 5104
HGNC HGNC:8723
Ensembl ENSG00000188488
Vega OTTHUMG00000170860
UCSC uc059eta.1
GO terms: 31 records
GO Description Category LogP Number of genes Detail
GO:0002020 protease binding GO Molecular Functions -28.8254555 31 More
GO:0004857 enzyme inhibitor activity GO Molecular Functions -18.4005452 35 More
GO:0004866 endopeptidase inhibitor activity GO Molecular Functions -20.0646267 27 More
GO:0004867 serine-type endopeptidase inhibitor activity GO Molecular Functions -8.20238048 12 More
GO:0005539 glycosaminoglycan binding GO Molecular Functions -36.7680176 44 More
GO:0005543 phospholipid binding GO Molecular Functions -6.61792344 45 More
GO:0007009 plasma membrane organization GO Biological Processes -3.91866373 17 More
GO:0007276 gamete generation GO Biological Processes -2.03816629 18 More
GO:0008201 heparin binding GO Molecular Functions -33.5542939 37 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0010466 negative regulation of peptidase activity GO Biological Processes -24.1438543 35 More
GO:0010951 negative regulation of endopeptidase activity GO Biological Processes -24.7873219 35 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030414 peptidase inhibitor activity GO Molecular Functions -19.6181890 27 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031091 platelet alpha granule GO Cellular Components -43.3287145 36 More
GO:0031406 carboxylic acid binding GO Molecular Functions -5.96500660 23 More
GO:0033293 monocarboxylic acid binding GO Molecular Functions -4.50166323 13 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043177 organic acid binding GO Molecular Functions -5.71225789 20 More
GO:0045861 negative regulation of proteolysis GO Biological Processes -27.9905009 43 More
GO:0051346 negative regulation of hydrolase activity GO Biological Processes -26.0030636 42 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0061134 peptidase regulator activity GO Molecular Functions -19.3582235 29 More
GO:0061135 endopeptidase regulator activity GO Molecular Functions -19.1908633 27 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:1901681 sulfur compound binding GO Molecular Functions -28.2504512 39 More
GO:1904090 peptidase inhibitor complex GO Cellular Components -5.67855223 6 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04610 Complement and coagulation cascades KEGG Pathway -50.1154932 39 More
Drug-Gene interaction
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Related drugs: 4 records
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
plasma serine protease inhibitor proteomics myocardial infarction[diagnosis] myocardial infarction Carroll VA et al. Arterioscler Thromb Vasc Biol. 1997
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